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Symbol
Name
ID
Hbs1l
Hbs1-like (S. cerevisiae)
MGI:1891704
Phenotype annotations related to hematopoietic system
Darker colors indicate more annotations
Human Phenotypes
Abnormal hemoglobin
Reduced beta/alpha synthesis ratio
Anemia
Hypochromic microcytic anemia
Microcytic anemia
Venous thrombosis
Thrombocytopenia
Splenomegaly
Disease(s) Associated with HBS1L
beta thalassemia

Mouse Phenotypes
increased mean corpuscular hemoglobin
thrombocytosis
increased mean platelet volume
decreased Langerhans cell number
decreased mature B cell number
increased memory CD4-positive, CD25-positive, alpha-beta regulatory T cell number
increased CD4-positive, CD25-positive, alpha-beta regulatory T cell number
increased CD4-positive, alpha-beta memory T cell number
decreased effector memory CD8-positive, alpha-beta T cell number
increased effector memory CD8-positive, alpha-beta T cell number
decreased memory-marker CD4-negative NK T cell number
decreased T-helper cell number
increased CD5-positive gamma-delta T cell number
increased regulatory T cell number
decreased monocyte cell number
increased leukocyte cell number
Availability Mouse Genotype
Hbs1ltm1a(KOMP)Wtsi/Hbs1ltm1a(KOMP)Wtsi

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory